Posted by: Thixia | March 13, 2008

Study – neurogenic bowel dysfunction

Treatment of Treatment of neurogenic bowel dysfunction using transanal irrigation: a multicenter Italian study

Study design:

Thirty-six patients with unsatisfactory treatment of neurogenic bowel dysfunctions (NBD) were enrolled from Spinal Units and Rehabilitation Centers in Italy. Treatment was for 3 weeks using a newly developed integrated system with an enema continence catheter for transanal irrigation.

Objectives:

To evaluate the effects of Peristeen Anal Irrigation on NBD and patient quality of life (QoL).

Setting:

Italy.

Methods:

Lesion level, ambulatory status and hand functionality were determined in all patients. NBD symptoms and QoL were evaluated before and after treatment, using a specific questionnaire. Statistical analysis was performed using McNemar Test and Sign Test.

Results:

36 patients were enrolled, and
32 patients completed the study.
28.6% of patients reduced or eliminated their use of pharmaceuticals At the end of the treatment,.
24 patients became less dependent on their caregiver.

There was a significant increase in patients’ opinion of their intestinal functionality (P=0.001), QoL score (P=0.001) and their answers regarding their degree of satisfaction (P=0.001). A successful outcome was recorded for 68% of patients with fecal incontinence, and for 63% of patients with constipation.
Conclusion:

Peristeen Anal Irrigation is a simple therapeutic method for managing NBD and improving QoL. It should be considered as the treatment of choice for NBD, playing a role in the neurogenic bowel analogous to that of intermittent clean catheterization in bladder treatment.

Treatment of neurogenic bowel dysfunction using transanal irrigation: a multicenter Italian study
1 Neuro-Urology Spinal Unit, University of Florence, Florence, Italy
2 Neurourology and Urodynamics Unit, Bambino Gesù Children’s Hospital, Rome, Italy
3 Spinal Unit, CTO Hospital, Rome, Italy
4 Urologic Unit, Villa delle Ginestre Hospital, Palermo, Italy
5 Spina Bifida Unit, Hospital of Vicenza, Vicenza, Italy
6 Pediatric Surgery Department, Giannina Gaslini Institute, Genova, Italy
7 Spinal Unit, Niguarda Hospital, Milan, Italy
8 Rehabilitation Institute, Caraglio, Italy
9 Montecatone Rehabilitation Institute, Imola, Italy
10 Gervasutta Rehabilitation Institute, Udine, Italy

Published online 4 March 2008.

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